Benzenepropanoic acid, 2-bromo-β-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (βS)- - Names and Identifiers
Benzenepropanoic acid, 2-bromo-β-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (βS)- - Physico-chemical Properties
Molecular Formula | C24H20BrNO4
|
Molar Mass | 466.32 |
Storage Condition | 2-8°C |
Benzenepropanoic acid, 2-bromo-β-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-, (βS)- - Introduction
Fmoc-S-3-Amino-3-(2-bromo-phenyl)-propionic acid is an organic compound with the chemical formula C₂ H₂ BrNO₂ S.
Nature:
Fmoc-S-3-Amino-3-(2-bromo-phenyl)-propionic acid is a white to off-white solid. It has a high melting point and relative molecular mass. It is insoluble in water at room temperature, but soluble in some organic solvents, such as dichloromethane, dimethyl sulfoxide and chloroform.
Use:
Fmoc-S-3-Amino-3-(2-bromo-phenyl)-propionic acid is an important reagent in peptide chemistry. It is commonly used as protecting groups and coupling reagents in peptide synthesis. It has a protective effect on the amino group, and can be introduced in the synthesis of specific groups to facilitate the reaction and separation, so as to control the synthesis and adjustment of peptide molecules.
Preparation Method:
The preparation of Fmoc-S-3-Amino-3-(2-bromo-phenyl)-propionic acid can be achieved through a synthetic route. A common synthetic method is the reaction of 3-amino -3-(2-bromophenyl) propionic acid with Fmoc-Cl (fluorenylformyl chloride) under basic conditions to give the desired product. The preparation process requires attention to the control of reaction conditions and the improvement of the purity and yield of the product.
Safety Information:
Fmoc-S-3-Amino -3-(2-bromophenyl) propionic acid is an organic compound and should be handled under appropriate laboratory conditions. Wear personal protective equipment such as lab gloves and goggles during use and handling. In addition, it should be stored in a dry, well-ventilated place to avoid contact with oxidants or other chemicals. In case of skin contact or inhalation, wash immediately or seek medical assistance. When storing and handling, refer to the relevant safety data sheets and operating manuals.
Last Update:2024-04-10 22:29:15